索引超出了数组界限。 文章摘要
|本期目录/Table of Contents|

[1]高彦淳,朱奕,张长青,等.淫羊藿苷治疗激素性股骨头坏死分子机制研究进展[J].国际骨科学杂志,2024,04:257-260.
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淫羊藿苷治疗激素性股骨头坏死分子机制研究进展(PDF)

《国际骨科学杂志》[ISSN:1673-7083/CN:31-1952/R]

期数:
2024年04期
页码:
257-260
栏目:
综述
出版日期:
2024-07-20

文章信息/Info

Title:
-
作者:
高彦淳; 朱奕; 张长青; 傅德皓; 姜晨轶
200233， 上海交通大学医学院附属第六人民医院骨科
Author(s):
-
关键词:
股骨头坏死; 淫羊藿苷; 糖皮质激素; 内皮细胞; 间充质干细胞; 成骨细胞
Keywords:
-
分类号:
-
DOI:
10.3969/j.issn.1673-7083.2024.04.009
文献标识码:
-
摘要:
淫羊藿苷在治疗激素性股骨头坏死方面的研究取得了显著进展。淫羊藿苷可通过提高促血管生成因子表达及抑制炎性因子，减少血管损伤，保护骨内血管的完整性。同时，淫羊藿苷能减少骨细胞凋亡，抑制骨髓脂肪细胞增生，促进局部骨修复，延缓病情进展。淫羊藿苷还可以通过促进成骨相关基因的表达，抑制脂肪分化，并通过表观遗传机制，发挥其治疗股骨头坏死的作用。此外，淫羊藿苷能通过激活相关信号通路，逆转缺氧引起的不良影响，保护成骨细胞功能。未来研究应深入解析淫羊藿苷在不同细胞类型间的相互作用及其在免疫调节中的作用机制，以全面了解其在治疗激素性股骨头坏死中的分子机制。该文就淫羊藿苷治疗激素性股骨头坏死分子机制研究进展进行综述。
Abstract:
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参考文献/References

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备注/Memo

备注/Memo:
基金项目：国家自然科学基金（82070911）
通信作者：傅德皓 E-mail: fudehao@sjtu.edu.cn 姜晨轶 E-mail: jiangchenyi716@163.com
更新日期/Last Update: 2024-07-20