[1]张运恒,王轩,李毅.诱导多能干细胞在骨关节炎治疗中的应用进展[J].国际骨科学杂志,2023,05:318-320,331.
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诱导多能干细胞在骨关节炎治疗中的应用进展(PDF)
《国际骨科学杂志》[ISSN:1673-7083/CN:31-1952/R]
- 期数:
- 2023年05期
- 页码:
- 318-320,331
- 栏目:
- 综述
- 出版日期:
- 2023-09-30
文章信息/Info
- Title:
- -
- Author(s):
- -
- Keywords:
- -
- 分类号:
- -
- DOI:
- 10.3969/j.issn. 1673-7083.2023.05.011
- 文献标识码:
- -
- 摘要:
- 骨关节炎（OA）是一种常见的慢性关节疾病，以关节软骨退行性变和继发性骨质增生为特点，主要影响 老年人，引起关节疼痛、僵硬等症状，严重者可发生关节畸形甚至残疾。目前OA 治疗多以疼痛管理和关节置换为主， 不能达到修复受损软骨或恢复组织稳态的目的。诱导多能干细胞(iPSC）具有很强的向软骨细胞分化的潜能，且具有 可通过对体细胞重编程获得、来源较多、不涉及伦理问题等特点。iPSC 的出现为软骨修复提供了新的途径，并有望 在OA 早期治疗中发挥重要作用。该文就iPSC 在OA 治疗中的应用进展进行综述。
- Abstract:
- -
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备注/Memo
- 备注/Memo:
- 通信作者：李毅 E-mail: tongrenly@163.com
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