索引超出了数组界限。 文章摘要
|本期目录/Table of Contents|

[1]韩博,蔡闯,崔学文,等.外泌体联合可注射生物材料治疗脊髓损伤[J].国际骨科学杂志,2022,06:362-366.
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外泌体联合可注射生物材料治疗脊髓损伤(PDF)

《国际骨科学杂志》[ISSN:1673-7083/CN:31-1952/R]

期数:
2022年06期
页码:
362-366
栏目:
综述
出版日期:
2022-12-01

文章信息/Info

Title:
-
文章编号:
10.3969/j.issn.1673-7083.2022.06.009
作者:
韩博;蔡闯;崔学文;
212001 江苏镇江， 江苏大学附属医院脊柱二科
Author(s):
-
关键词:
脊髓损伤; 可注射生物材料; 水凝胶; 纳米颗粒; 复合材料; 外泌体; 间充质干细胞
Keywords:
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分类号:
-
DOI:
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文献标识码:
-
摘要:
脊髓损伤（SCI）常与高能量机械冲击有关，而现有治疗方法往往无法取得预期效果。多项研究均表明，采 用来源于骨髓间充质干细胞的外泌体（MSC-Exo）治疗SCI 效果确切。将负载MSC-Exo 的可注射材料直接注射到病 变部位，使之在促进SCI 部位修复的同时充当修复支架，已成为优化外泌体治疗SCI 效果的新方向。与传统方法相比， 使用可注射材料优势更明显，即通过微创技术将药物直接注射到靶组织中可以避免二次损伤，保证药物作用时间长 而稳定，并可有效填充病变腔和诱导桥接效应，从而实现SCI 组织的有效修复。该文将就近年来负载MSC-Exo 的可 注射材料治疗SCI 的研究进展进行综述，总结可注射材料的优点，为后续研究提供参考。
Abstract:
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备注/Memo

备注/Memo:
基金项目： 国家自然科学基金（51403086）
通信作者： 崔学文 E-mail: cui5898@sohu.com
更新日期/Last Update: 2022-12-01