索引超出了数组界限。 文章摘要
|本期目录/Table of Contents|

[1]张晋宁,杨天翔,张博文,等.转化生长因子-β信号转导通路与骨关节炎[J].国际骨科学杂志,2021,02:97-101.
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转化生长因子-β信号转导通路与骨关节炎(PDF)

《国际骨科学杂志》[ISSN:1673-7083/CN:31-1952/R]

期数:
2021年02期
页码:
97-101
栏目:
综述
出版日期:
2021-04-20

文章信息/Info

Title:
-
作者:
张晋宁; 杨天翔; 张博文; 程萌旗; 陈德胜
750004 银川, 宁夏医科大学临床医学院(张晋宁、杨天翔、张博文); 200233, 上海交通大学附属第六人民医院关节外科(程萌旗); 750004 银川, 宁夏医科大学总医院骨科(陈德胜)
Author(s):
-
关键词:
转化生长因子-β;  信号转导通路;  骨关节炎;  关节软骨
Keywords:
-
分类号:
-
DOI:
10.3969/j.issn.1673-7083.2021.02.008
文献标识码:
-
摘要:
骨关节炎是一种慢性老年性骨关节病变,临床表现为软骨破坏、软骨下骨硬化、滑膜增生、骨赘形成等。骨关节炎中晚期患者会出现关节疼痛、僵硬,甚至关节功能降低或丧失。转化生长因子(TGF)-β对关节软骨生长发育及软骨分化有一定的调控作用,是维持关节软骨及周围组织稳定状态的关键。TGF-β信号转导通路可影响软骨细胞分化与生长、软骨下骨重塑、滑膜炎症改变。该文就TGF-β信号转导通路对骨关节炎机制的影响作一综述。
Abstract:
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参考文献/References

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备注/Memo

备注/Memo:
基金项目: 国家自然科学基金(82060408、81760405、81760395)、宁夏自治区自然科学基金(2018AAC02013)、宁夏医科大学校级课题(XZ2018014)、宁夏高等学校一流学科建设(宁夏医科大学国内一流建设学科临床医学)资助项目(NXYLXK2017A05)
更新日期/Last Update: 2021-04-20