索引超出了数组界限。 文章摘要
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[1]原静晨,宋洁富,王小健,等.肠道菌群影响骨代谢的机制研究进展[J].国际骨科学杂志,2021,02:89-92.
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肠道菌群影响骨代谢的机制研究进展(PDF)

《国际骨科学杂志》[ISSN:1673-7083/CN:31-1952/R]

期数:
2021年02期
页码:
89-92
栏目:
综述
出版日期:
2021-04-20

文章信息/Info

Title:
-
作者:
原静晨; 宋洁富; 王小健; 程杰
030012 太原, 山西医科大学附属人民医院脊柱外科(原静晨、宋洁富、王小健); 030012 太原, 山西医科大学附属人民医院胃肠外科(程杰)
Author(s):
-
关键词:
肠道菌群;  骨代谢;  骨质疏松症;  影响机制
Keywords:
-
分类号:
-
DOI:
10.3969/j.issn.1673-7083.2021.02.006
文献标识码:
-
摘要:
肠道菌群在维持人体健康中起主要作用。肠道菌群与骨代谢联系密切,其对骨骼形成或破坏的作用机制可由免疫系统介导,可通过调节破骨细胞诱导因子、调节性T细胞表达以及辅助性T细胞17分化等途径增强或抑制破骨细胞活性。肠道菌群也可以影响雌激素、胰岛素样生长因子-1、5-羟色胺等内分泌激素,从而影响骨骼健康。肠道菌群还可通过自身及其代谢产物的变化直接或间接影响骨代谢。对肠道菌群影响骨代谢机制的探讨,有助于研究肠道微生物在骨代谢中的作用,为难治性骨质疏松症的治疗提供新思路。
Abstract:
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参考文献/References

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备注/Memo

备注/Memo:
基金项目: 山西省重点研发计划项目(201803D31160)
通信作者: 宋洁富 E-mail: 13803466607@qq.com
更新日期/Last Update: 2021-04-20