索引超出了数组界限。 文章摘要
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[1]高子浚,张皓,李春霖,等.氧化应激影响移植后皮瓣愈合的研究进展[J].国际骨科学杂志,2021,01:35-39.
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氧化应激影响移植后皮瓣愈合的研究进展(PDF)

《国际骨科学杂志》[ISSN:1673-7083/CN:31-1952/R]

期数:
2021年01期
页码:
35-39
栏目:
综述
出版日期:
2021-02-10

文章信息/Info

Title:
-
作者:
高子浚张皓李春霖邓国英
201620, 上海交通大学附属第一人民医院创伤中心(高子浚、张皓、李春霖、邓国英); 200025, 上海交通大学医学院一院临床医学院(高子浚、张皓)
Author(s):
-
关键词:
氧化应激 移植后皮瓣愈合 活性氧自由基
Keywords:
-
分类号:
-
DOI:
10.3969/j.issn.1673-7083.2021.01.009
文献标识码:
-
摘要:
皮瓣移植术是临床修复组织缺损、畸形等的一种常用方法,移植后皮瓣成活的问题仍有待解决。术后皮瓣愈合情况受多种因素影响,主要与氧化应激过程及其产物活性氧自由基(ROS)密切相关。氧化应激影响移植后皮瓣愈合情况的主要途径有①ROS直接攻击细胞造成细胞衰老、损伤和凋亡; ②炎症反应; ③影响血供等。药物干预通过清除过量ROS,抑制细胞凋亡,减轻炎症反应和改善血供状况等途径促进移植后皮瓣愈合,可有效提高皮瓣移植术后的皮瓣成活率。氧化应激是当下研究热点之一,但氧化应激与移植后皮瓣愈合相关性的研究相对较少。该文对氧化应激对皮瓣愈合影响的研究进展作一综述。
Abstract:
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备注/Memo

备注/Memo:
基金项目: 上海交通大学转化医学交叉研究基金(ZH2018QNA20)、上海市科技人才项目(19YF1440000)
通信作者: 邓国英 E-mail: parisdeng2012@hotmail.com
更新日期/Last Update: 2021-02-10