索引超出了数组界限。 文章摘要
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[1]蔡同川,张亮.白藜芦醇与椎间盘退变性疾病[J].国际骨科学杂志,2021,01:22-25.
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白藜芦醇与椎间盘退变性疾病(PDF)

《国际骨科学杂志》[ISSN:1673-7083/CN:31-1952/R]

期数:
2021年01期
页码:
22-25
栏目:
综述
出版日期:
2021-02-10

文章信息/Info

Title:
-
作者:
蔡同川张亮
116000, 大连医科大学研究生院(蔡同川); 225001, 大连医科大学扬州临床医学院(张亮)
Author(s):
-
关键词:
椎间盘退变性疾病 白藜芦醇 髓核细胞 自噬 凋亡
Keywords:
-
分类号:
-
DOI:
10.3969/j.issn.1673-7083.2021.01.006
文献标识码:
-
摘要:
椎间盘退变性疾病发生机制主要包括机械应力、高糖、炎症反应、氧化应激和细胞衰老导致的髓核细胞退变。目前研究发现,白藜芦醇可通过影响椎间盘髓核细胞自噬、凋亡、衰老及细胞外基质表达,达到保护及修复髓核细胞的目的,因此白藜芦醇在椎间盘退变性疾病中的作用值得研究。该文就白藜芦醇对椎间盘退变性疾病中髓核细胞的保护作用及其作用机制进行综述。
Abstract:
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参考文献/References

[1] Jonsson E, Olafsson G, Fritzell P, et al. A profile of low back pain: treatment and costs associated with patients referred to orthopedic specialists in sweden[J]. Spine(Phila Pa 1976), 2017, 42(17): 1302-1310.
[2] Almeida M, Saragiotto B, Maher CG. Primary care management of non-specific low back pain: key messages from recent clinical guidelines[J]. Med J Aust, 2018, 209(5): 235.
[3] Oyenihi OR, Oyenihi AB, Adeyanju AA, et al. Antidiabetic effects of resveratrol: the way forward in its clinical utility[J]. J Diabetes Res, 2016, 2016: 9737483.
[4] Wang J, Gao JS, Chen JW, et al. Effect of resveratrol on cartilage protection and apoptosis inhibition in experimental osteoarthritis of rabbit[J]. Rheumatol Int, 2012, 32(6): 1541-1548.
[5] Zhang C, Yuan W, Fang J, et al. Efficacy of resveratrol supplementation against non-alcoholic fatty liver disease: a meta-analysis of placebo-controlled clinical trials[J]. PLoS One, 2016, 11(8): e0161792.
[6] Wang WJ, Yu XH, Wang C, et al. MMPs and ADAMTSs in intervertebral disc degeneration[J]. Clin Chim Acta, 2015, 448: 238-246.
[7] Hwang MH, Son HG, Lee JW, et al. Photobiomodulation of extracellular matrix enzymes in human nucleus pulposus cells as a potential treatment for intervertebral disk degeneration[J]. Sci Rep, 2018, 8(1): 11654.
[8] Gao J, Zhang Q, Song L. Resveratrol enhances matrix biosynthesis of nucleus pulposus cells through activating autophagy via the PI3K/Akt pathway under oxidative damage[J]. Biosci Rep, 2018, 38(4): BSR20180544.
[9] Wang W, Li P, Xu J, et al. Resveratrol attenuates high glucose-induced nucleus pulposus cell apoptosis and senescence through activating the ROS-mediated PI3K/Aktpathway[J]. Biosci Rep, 2018, 38(2): BSR20171454.
[10] Li YR, Li S, Lin CC. Effect of resveratrol and pterostilbene on aging and longevity[J]. Biofactors, 2018, 44(1): 69-82.
[11] Han X, Leng X, Zhao M, et al. Resveratrol increases nucleus pulposus matrix synthesis through activating the PI3K/Akt signaling pathway under mechanical compression in a disc organ culture[J]. Biosci Rep, 2017, 37(6):BSR20171319.
[12] Zhang Z, Wen F, He C, et al. Resveratrol attenuates mechanical compression-induced nucleus pulposus cell apoptosis through regulating the ERK1/2 signaling pathway in a disc organ culture[J]. Biosci Rep, 2018, 38(2):BSR20171703.
[13] 沈皆亮, 胡侦明, 钟小明, 等. 白藜芦醇通过上调SIRT1促进退变髓核细胞胞外基质合成[J]. 细胞与分子免疫学杂志, 2012, 28(11): 1146-1150.
[14] 刘沪喆, 沈皆亮, 周浩, 等. 白藜芦醇通过Wnt/β-catenin信号通路调控髓核细胞细胞外基质表达[J]. 中国修复重建外科杂志, 2018, 32(4): 476-483.
[15] Wang XH, Zhu L, Hong X, et al. Resveratrol attenuated TNF-α-induced MMP-3 expression in human nucleus pulposus cells by activating autophagy via AMPK/SIRT1 signaling pathway[J]. Exp Biol Med(Maywood), 2016, 241(8): 848-853.
[16] Wu JW, Wang JJ, Chen JB, et al. Resveratrol could reverse the expression of SIRT1 and MMP-1 in vitro[J]. Genet Mol Res, 2015, 14(4): 12386-12393.
[17] 沈皆亮, 胡侦明, 钟小明, 等. 白藜芦醇恢复去分化正常髓核细胞表型的实验研究[J]. 中国修复重建外科杂志, 2013, 27(5): 547-553.
[18] Revuelta M, Matheu A. Autophagy in stem cell aging[J]. Aging Cell, 2017, 16(5): 912-915.
[19] Zhang B, Xu L, Zhuo N, et al. Resveratrol protects against mitochondrial dysfunction through autophagy activation in human nucleus pulposus cells[J]. Biochem Biophys Res Commun, 2017, 493(1): 373-381.
[20] Guo J, Shao M, Lu F, et al. Role of Sirt1 plays in nucleus pulposus cells and intervertebral disc degeneration[J]. Spine(Phila Pa 1976), 2017, 42(13): E757-E766.
[21] Barger JL, Vann JM, Cray NL, et al. Identification of tissue-specific transcriptional markers of caloric restriction in the mouse and their use to evaluate caloric restriction mimetics[J]. Aging Cell, 2017, 16(4): 750-760.
[22] Patil P, Niedernhofer LJ, Robbins PD, et al. Cellular senescence in intervertebral disc aging and degeneration[J]. Curr Mol Biol Rep, 2018, 4(4): 180-190.
[23] An JL, Zhang W, Zhang J, et al. Vitamin D improves the content of TGF-beta and IGF-1 in intervertebral disc of diabetic rats[J]. Exp Biol Med(Maywood), 2017, 242(12): 1254-1261.
[24] Agius R, Galea R, Fava S. Bone mineral density and intervertebral disc height in type 2 diabetes[J]. J Diabetes Complications, 2016, 30(4): 644-650.
[25] Kaplan M, Arici L, Ozturk S, et al. A comparison of the type IX collagen levels of the intervertebral disc materials in diabetic and non-diabetic patients who treated with lumbar microdiscectomy[J]. Eur Spine J, 2018, 27(1): 214-221.
[26] Yang SD, Ma L, Yang DL, et al. Combined effect of 17β-estradiol and resveratrol against apoptosis induced by interleukin-1β in rat nucleus pulposus cells via PI3K/Akt/caspase-3 pathway[J]. PeerJ, 2016, 4: e1640.
[27] Buckley CT, Hoyland JA, Fujii K, et al. Critical aspects and challenges for intervertebral disc repair and regeneration-Harnessing advances in tissue engineering[J]. JOR Spine, 2018, 1(3): e1029.
[28] Li K, Li Y, Mi J, et al. Resveratrol protects against sodium nitroprusside induced nucleus pulposus cell apoptosis by scavenging ROS[J]. Int J Mol Med, 2018, 41(5): 2485-2492.
[29] Xia X, Guo J, Lu F, et al. SIRT1 plays a protective role in intervertebral disc degeneration in a puncture-induced rodent model[J]. Spine(Phila Pa 1976), 2015, 40(9): E515-E524.
[30] Lin B, Yu H, He Y, et al. Protective effects of resveratrol on autologous nucleus pulposus model of radiculopathy[J]. Exp Ther Med, 2016, 12(6): 3917-3922.
[31] Shen J, Zhuo N, Xu S, et al. Resveratrol delivery by ultrasound-mediated nanobubbles targeting nucleus pulposus cells[J]. Nanomedicine(Lond), 2018, 13(12): 1433-1446.

备注/Memo

备注/Memo:
基金项目: 江苏省青年医学重点人才项目(QNRC2016342)、江苏省妇幼健康科研重点资助项目(F201801)、江苏省高层次卫生人才“六个一工程”拔尖人才科研项目(LGY2019035)
通信作者: 张亮 E-mail: zhangliang6320@sina.com
更新日期/Last Update: 2021-02-10