索引超出了数组界限。 文章摘要
|本期目录/Table of Contents|

[1]孔令驰 关俊杰 康庆林.miRNA在激素性股骨头坏死中的作用研究进展[J].国际骨科学杂志,2019,04:224-228.
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miRNA在激素性股骨头坏死中的作用研究进展(PDF)

《国际骨科学杂志》[ISSN:1673-7083/CN:31-1952/R]

期数:
2019年04期
页码:
224-228
栏目:
综述
出版日期:
2019-08-09

文章信息/Info

Title:
-
作者:
孔令驰 关俊杰 康庆林
200233, 上海交通大学附属第六人民医院骨科
Author(s):
-
关键词:
激素性股骨头坏死;  微RNA;  表达调控;  信号通路
Keywords:
-
分类号:
-
DOI:
10.3969/j.issn.1673-7083.2019.04.008
文献标识码:
-
摘要:
激素性股骨头坏死(SONFH)是使用糖皮质激素导致的无菌性股骨头坏死。其可能的发病机制包括激素诱导的成骨细胞凋亡、成脂与成骨分化失衡及股骨头微循环受损等。近年来,微RNA(miRNA)逐渐成为非编码RNA领域的研究热点,部分miRNA已被证实与SONFH的发病机制密切相关。该文拟从SONFH患者或动物模型的miRNA表达失调、miRNA对SONFH进展的调控作用及miRNA对SONFH的潜在诊疗价值等方面作一综述,为SONFH的预防和治疗提供新思路。
Abstract:
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参考文献/References

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备注/Memo

备注/Memo:
基金项目: 国家自然科学基金面上项目(81572121)
通信作者: 康庆林 E-mail: orthokang@163.com
更新日期/Last Update: 2019-08-09