索引超出了数组界限。 文章摘要
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[1]彭咲远 王启阳 高彦淳 冯勇 张长青.血清淀粉样蛋白A在骨科领域中的应用[J].国际骨科学杂志,2019,02:108-112.
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血清淀粉样蛋白A在骨科领域中的应用(PDF)

《国际骨科学杂志》[ISSN:1673-7083/CN:31-1952/R]

期数:
2019年02期
页码:
108-112
栏目:
综述
出版日期:
2019-05-08

文章信息/Info

Title:
-
作者:
彭咲远 王启阳 高彦淳 冯勇 张长青
200233, 上海交通大学附属第六人民医院骨科
Author(s):
-
关键词:
血清淀粉样蛋白A;  高密度脂蛋白;  急性炎症反应;  骨科疾病;  骨肿瘤
Keywords:
-
分类号:
-
DOI:
10.3969/j.issn.1673-7083.2019.02.010
文献标识码:
-
摘要:
血清淀粉样蛋白A(SAA)是一类急性相蛋白,主要与高密度脂蛋白结合而发挥作用。SAA在机体多种组织内均有转录和表达,结合多种不同细胞因子,多途径参与并影响机体病理和生理过程。SAA表达改变不仅出现在炎性疾病中,更是出现在一些肿瘤等非炎性疾病中。SAA在多研究中被提及可以作为骨关节炎症和骨肿瘤的生物标志物。尽管已有研究涉及SAA抑制破骨细胞分化和成骨分化刺激以及破坏骨与关节软骨,但炎症-骨代谢-脂代谢之间联系的建立以及其中病理生理机制尚不清楚。该文就SAA在骨科学领域中的应用作一综述。
Abstract:
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参考文献/References


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备注/Memo

备注/Memo:
作者单位: 200233, 上海交通大学附属第六人民医院骨科
通信作者: 张长青 E-mail: zhangcq@sjtu.edu.cn
更新日期/Last Update: 2019-05-09