索引超出了数组界限。 文章摘要
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[1]陈亦轩,朱道宇,殷俊辉,等.酒精性股骨头坏死研究进展[J].国际骨科学杂志,2018,01:28-32.
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酒精性股骨头坏死研究进展(PDF)

《国际骨科学杂志》[ISSN:1673-7083/CN:31-1952/R]

期数:
2018年01期
页码:
28-32
栏目:
综述
出版日期:
2018-01-30

文章信息/Info

Title:
-
作者:
陈亦轩; 朱道宇; 殷俊辉; 高悠水; 张长青
200025, 上海交通大学医学院(陈亦轩、朱道宇); 200233, 上海交通大学附属第六人民医院骨科(陈亦轩、朱道宇、高悠水、张长青); 200233, 上海市四肢显微外科研究所(殷俊辉、张长青)
Author(s):
-
关键词:
酒精;  股骨头坏死;  骨稳态;  代谢
Keywords:
-
分类号:
-
DOI:
10.3969/j.issn.1673-7083.2018.01.008
文献标识码:
A
摘要:
流行病学研究显示,饮酒是非创伤性股骨头坏死常见的危险因素之一,存在显著的剂量-效应关系。在酒精性股骨头坏死发生过程中,常表现出脂代谢和炎症反应的异常。酒精可通过多种途径抑制骨形成,促进骨吸收,破坏骨稳态。遗传与表观遗传修饰都可在酒精代谢中发挥作用,与酒精性股骨头坏死也密切相关。酒精对人体多系统可产生复杂的生物学效应,因而酒精性股骨头坏死的发生是多因素且个体化的。
Abstract:
-

参考文献/References

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备注/Memo

备注/Memo:
基金项目: 国家自然科学基金(81672143)
通信作者: 高悠水 E-mail: gaoyoushui@163.com
更新日期/Last Update: 2018-01-30