[1]陈胜,邓享誉,马凯歌,等.干细胞与髓核细胞相互作用及其机制的研究进展[J].国际骨科学杂志,2017,06:376-379.
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干细胞与髓核细胞相互作用及其机制的研究进展(PDF)
《国际骨科学杂志》[ISSN:1673-7083/CN:31-1952/R]
- 期数:
- 2017年06期
- 页码:
- 376-379
- 栏目:
- 综述
- 出版日期:
- 2017-11-30
文章信息/Info
- Title:
- -
- Author(s):
- -
- Keywords:
- -
- 分类号:
- -
- DOI:
- 10.3969/j.issn.1673-7083.2017.06.010
- 文献标识码:
- -
- 摘要:
- 近年来,以干细胞为核心的生物治疗技术成为修复椎间盘退行性变(IVDD)的主要手段,其主要通过干细胞与椎间盘内髓核细胞的相互作用修复IVDD。髓核细胞通过影响干细胞形态,促进干细胞向椎间盘迁移和募集,并促进其向髓核细胞分化。干细胞可以增强髓核细胞的合成代谢,减少分解代谢,抑制炎性反应,并能促进髓核细胞增殖,减少细胞凋亡。干细胞与髓核细胞相互作用的机制主要为直接接触和旁分泌。该文对干细胞与髓核细胞相互作用及其机制的研究进展作一综述。
- Abstract:
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参考文献/References
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备注/Memo
- 备注/Memo:
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基金项目: 国家重点研发计划重点专项(2016YFC1100100)、国家自然科学基金重大研究计划(91649204)
通信作者: 邵增务 E-mail: SZWpro@163.com
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