索引超出了数组界限。 文章摘要
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[1]陶诗聪,郭尚春,张长青.长链非编码RNA在骨关节炎中的作用[J].国际骨科学杂志,2016,06:378-382,387.
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长链非编码RNA在骨关节炎中的作用(PDF)

《国际骨科学杂志》[ISSN:1673-7083/CN:31-1952/R]

期数:
2016年06期
页码:
378-382,387
栏目:
综述
出版日期:
2016-11-25

文章信息/Info

Title:
-
作者:
陶诗聪郭尚春张长青
200233, 上海交通大学附属第六人民医院骨科(陶诗聪、张长青)、上海交通大学附属第六人民医院四肢显微外科研究所(郭尚春、张长青); 200025, 上海交通大学医学院(陶诗聪)
Author(s):
-
关键词:
长链非编码RNA 骨关节炎 表观遗传
Keywords:
-
分类号:
-
DOI:
10.3969/j.issn.1673-7083.2016.06.009
文献标识码:
-
摘要:
长链非编码RNA(LncRNA)在软骨发育及骨关节炎(OA)病理进程中起到了重要的调控作用。LncRNA可以调控软骨细胞增殖、分化和凋亡,影响软骨细胞外基质分泌,通过调控基质金属蛋白酶分泌影响软骨细胞外基质降解,参与软骨炎症反应,在软骨退行性变的发生发展中发挥重要作用。该文就LncRNA在OA发生发展中的作用作一综述。
Abstract:
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参考文献/References

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备注/Memo

备注/Memo:
基金项目: 国家自然科学基金面上项目(81572239、81472066)、国家自然科学基金青年基金(81301589)作者单位: 200233, 上海交通大学附属第六人民医院骨科(陶诗聪、张长青)、上海交通大学附属第六人民医院四肢显微外科研究所(郭尚春、张长青); 200025, 上海交通大学医学院(陶诗聪)通信作者: 张长青 E-mail: zhangcq@sjtu.edu.cn
更新日期/Last Update: 2016-11-20